Flowering

Giovanna
Giovanna

Group Interests

The induction of flowering is a central event in the life cycle of plants. When timed correctly, it helps to ensure reproductive success, and therefore has adaptive value. Because of its importance, flowering is under the control of a complex genetic circuitry that integrates environmental and endogenous signals. Genetic analyses initially suggested the existence of distinct, genetically defined pathways that regulate flowering in response to a specific input. Over the last years, however, it has become apparent that many important flowering time genes are not regulated by single inputs, but rather integrate multiple, often contradictory signals to control the induction of flowering. This provides plants with a certain developmental plasticity in their timing of the floral transition. Work in our group has so far mostly aimed to understand the precise mechanisms that govern flowering time. To this end we employ a combination of molecular biology, genetic, and high-throughput sequencing (ChIP-seq, RNA-seq) techniques to unravel the transcription factor network that integrates diverse environmental signals in the model plant Arabidopsis thaliana. More recently we have adopted the INTACT, which allows the isolation of nuclei from defined tissues and cell types, to increase the temporal and spatial resolution of our analyses. A second focus of the group is directed at understanding how trehalose-6-phosphate (and sugar signals in general) are integrated into the canonical network that regulates flowering.

  • Integration of flowering time signals in Arabidopsis thaliana
  • Transcription factors & epigenetic control of flowering
  • Trehalose-6-phosphate signaling in flowering time regulation

The group has recently moved to the Umeå Plant Science Centre in Sweden. More information is available here.


Collaboration Partners

References

20.

Modulation of Ambient Temperature-Dependent Flowering in Arabidopsis thaliana by Natural Variation of FLOWERING LOCUS M

Lutz U., Pose D., Pfeifer M., Gundlach H., Hagmann J., Wang C., Weigel D., Mayer K. F., Schmid M. and Schwechheimer C.
PLoS Genet
(2015), 11(10) e1005588.
19.

Gibberellic acid signaling is required for ambient temperature-mediated induction of flowering in Arabidopsis thaliana

Galvao V. C., Collani S., Horrer D. and Schmid M.
Plant J
(2015), .
18.

Role of alternative pre-mRNA splicing in temperature signaling

Capovilla G., Pajoro A., Immink R. G. and Schmid M.
Curr Opin Plant Biol
(2015), 27 97-103.
17.

Control of flowering by ambient temperature

Capovilla G., Schmid M. and Pose D.
J Exp Bot
(2015), 66(1) 59-69.
16.

Regulation of flowering by trehalose-6-phosphate signaling in Arabidopsis thaliana

Wahl V., Ponnu J., Schlereth A., Arrivault S., Langenecker T., Franke A., Feil R., Lunn J. E., Stitt M. and Schmid M.
Science
(2013), 339(6120) 704-7.
15.

Regulation of temperature-responsive flowering by MADS-box transcription factor repressors

Lee J. H., Ryu H. S., Chung K. S., Pose D., Kim S., Schmid M. and Ahn J. H.
Science
(2013), 342(6158) 628-32.
14.

Temperature-dependent regulation of flowering by antagonistic FLM variants

Pose D., Verhage L., Ott F., Yant L., Mathieu J., Angenent G. C., Immink R. G. and Schmid M.
Nature
(2013), 503(7476) 414-7.
13.

Characterization of SOC1's central role in flowering by the identification of its upstream and downstream regulators

Immink R. G., Pose D., Ferrario S., Ott F., Kaufmann K., Valentim F. L., de Folter S., van der Wal F., van Dijk A. D., Schmid M. and Angenent G. C.
Plant Physiol
(2012), 160(1) 433-49.
12.

Gibberellin regulates the Arabidopsis floral transition through miR156-targeted SQUAMOSA promoter binding-like transcription factors

Yu S., Galvao V. C., Zhang Y. C., Horrer D., Zhang T. Q., Hao Y. H., Feng Y. Q., Wang S., Schmid M. and Wang J. W.
Plant Cell
(2012), 24(8) 3320-32.
11.

Spatial control of flowering by DELLA proteins in Arabidopsis thaliana

Galvao V. C., Horrer D., Kuttner F. and Schmid M.
Development
(2012), 139(21) 4072-82.
10.

Synteny-based mapping-by-sequencing enabled by targeted enrichment

Galvao V. C., Nordstrom K. J., Lanz C., Sulz P., Mathieu J., Pose D., Schmid M., Weigel D. and Schneeberger K.
Plant J
(2012), 71(3) 517-26.
9.

Regulation of flowering time: all roads lead to Rome

Srikanth A. and Schmid M.
Cell Mol Life Sci
(2011), 68(12) 2013-37.
8.

The control of developmental phase transitions in plants

Huijser P. and Schmid M.
Development
(2011), 138(19) 4117-29.
7.

Trehalose-6-phosphate: connecting plant metabolism and development

Ponnu J., Wahl V. and Schmid M.
Front Plant Sci
(2011), 2 70.
6.

Orchestration of the floral transition and floral development in Arabidopsis by the bifunctional transcription factor APETALA2

Yant L., Mathieu J., Dinh T. T., Ott F., Lanz C., Wollmann H., Chen X. and Schmid M.
Plant Cell
(2010), 22(7) 2156-70.
5.

The FANTASTIC FOUR proteins influence shoot meristem size in Arabidopsis thaliana

Wahl V., Brand L. H., Guo Y. L. and Schmid M.
BMC Plant Biol
(2010), 10 285.
4.

Just say no: floral repressors help Arabidopsis bide the time

Yant L., Mathieu J. and Schmid M.
Curr Opin Plant Biol
(2009), 12(5) 580-6.
3.

Repression of flowering by the miR172 target SMZ

Mathieu J., Yant L. J., Murdter F., Kuttner F. and Schmid M.
PLoS Biol
(2009), 7(7) e1000148.
2.

Export of FT protein from phloem companion cells is sufficient for floral induction in Arabidopsis

Mathieu J., Warthmann N., Kuttner F. and Schmid M.
Curr Biol
(2007), 17(12) 1055-60.
1.

Dissection of floral induction pathways using global expression analysis

Schmid M., Uhlenhaut N. H., Godard F., Demar M., Bressan R., Weigel D. and Lohmann J. U.
Development
(2003), 130(24) 6001-12.