The induction of flowering is a central event in the life cycle of plants. When timed correctly, it helps to ensure reproductive success, and therefore has adaptive value. Because of its importance, flowering is under the control of a complex genetic circuitry that integrates environmental and endogenous signals. Genetic analyses initially suggested the existence of distinct, genetically defined pathways that regulate flowering in response to a specific input. Over the last years, however, it has become apparent that many important flowering time genes are not regulated by single inputs, but rather integrate multiple, often contradictory signals to control the induction of flowering. This provides plants with a certain developmental plasticity in their timing of the floral transition. Work in our group has so far mostly aimed to understand the precise mechanisms that govern flowering time. To this end we employ a combination of molecular biology, genetic, and high-throughput sequencing (ChIP-seq, RNA-seq) techniques to unravel the transcription factor network that integrates diverse environmental signals in the model plant Arabidopsis thaliana. More recently we have adopted the INTACT, which allows the isolation of nuclei from defined tissues and cell types, to increase the temporal and spatial resolution of our analyses. A second focus of the group is directed at understanding how trehalose-6-phosphate (and sugar signals in general) are integrated into the canonical network that regulates flowering.
The group has recently moved to the Umeå Plant Science Centre in Sweden. More information is available here.
Modulation of Ambient Temperature-Dependent Flowering in Arabidopsis thaliana by Natural Variation of FLOWERING LOCUS M, , , , , , , , and
PLoS Genet (2015), 11(10) e1005588.
Gibberellic acid signaling is required for ambient temperature-mediated induction of flowering in Arabidopsis thaliana, , and
Plant J (2015), .
Role of alternative pre-mRNA splicing in temperature signaling, , and
Curr Opin Plant Biol (2015), 27 97-103.
Control of flowering by ambient temperature, and
J Exp Bot (2015), 66(1) 59-69.
Regulation of flowering by trehalose-6-phosphate signaling in Arabidopsis thaliana, , , , , , , , and
Science (2013), 339(6120) 704-7.
Regulation of temperature-responsive flowering by MADS-box transcription factor repressors, , , , , and
Science (2013), 342(6158) 628-32.
Temperature-dependent regulation of flowering by antagonistic FLM variants, , , , , , and
Nature (2013), 503(7476) 414-7.
Characterization of SOC1's central role in flowering by the identification of its upstream and downstream regulators, , , , , , , , , and
Plant Physiol (2012), 160(1) 433-49.
Gibberellin regulates the Arabidopsis floral transition through miR156-targeted SQUAMOSA promoter binding-like transcription factors, , , , , , , , and
Plant Cell (2012), 24(8) 3320-32.
Spatial control of flowering by DELLA proteins in Arabidopsis thaliana, , and
Development (2012), 139(21) 4072-82.
Synteny-based mapping-by-sequencing enabled by targeted enrichment, , , , , , , and
Plant J (2012), 71(3) 517-26.
Regulation of flowering time: all roads lead to Romeand
Cell Mol Life Sci (2011), 68(12) 2013-37.
The control of developmental phase transitions in plantsand
Development (2011), 138(19) 4117-29.
Trehalose-6-phosphate: connecting plant metabolism and development, and
Front Plant Sci (2011), 2 70.
Orchestration of the floral transition and floral development in Arabidopsis by the bifunctional transcription factor APETALA2, , , , , , and
Plant Cell (2010), 22(7) 2156-70.
The FANTASTIC FOUR proteins influence shoot meristem size in Arabidopsis thaliana, , and
BMC Plant Biol (2010), 10 285.
Just say no: floral repressors help Arabidopsis bide the time, and
Curr Opin Plant Biol (2009), 12(5) 580-6.
Repression of flowering by the miR172 target SMZ, , , and
PLoS Biol (2009), 7(7) e1000148.
Export of FT protein from phloem companion cells is sufficient for floral induction in Arabidopsis, , and
Curr Biol (2007), 17(12) 1055-60.
Dissection of floral induction pathways using global expression analysis, , , , , and
Development (2003), 130(24) 6001-12.