Haim Ashkenazy
Exposure to bacterial pathogens and symbionts plays a major role in shaping plant genomes through the course of evolution. My research focuses on identifying genomic signatures of plant-bacterial interactions in order to discover and understand plant adaptations to biotic stress. As a bioinformatician, I address these questions by developing computational methods, which take advantage of rich sequence data, such as population-level genomics. Specifically, I employ a comparative-genomics approach, which frames the analysis of sequence information in the context of the underlying evolutionary process. Homepage: http://haimashkenazy.wixsite.com/home
Research lines
- Plant evolutionary genomics
- Evolutionary dynamics of gene content in bacterial and plant genomes
- Co-evolution of plant-microbe interactions
- Comparative genomics and phylogenomics
Short vita
Selected publications
Journal articles
Multiple sequence alignment averaging improves phylogeny reconstruction Ashkenazy, H., Sela, I., Levy Karin, E., Landan, G., Pupko, T. Systematic Biology (2018).
ConSurf 2016: an improved methodology to estimate and visualize evolutionary conservation in macromolecules Ashkenazy, H. Abadi, S., Martz, E., Chay, O., Mayrose, I., Pupko, T., Ben-Tal, N. Nucleic Acids Res (2016), 44: W34
4-350.
GUIDANCE2: accurate detection of unreliable alignment regions accounting for the uncertainty of multiple parameters Sela, I.*, Ashkenazy, H.*, Katoh, K., Pupko, T. Nucleic Acids Res, (2015), 43: W7-14 (* Equal contribution).
Indel reliability in indel-based phlyogenetic inference Ashkenazy, H., Cohen, O., Pupko, T., Huchon, D. Genome Biol Evol, (2014), 6(12) : 3199-3209.
Books