Assembling Arabidopsis centromeres with HiFi reads

Collaboration with Ian Henderson (Cambridge):

Pushing the limits of HiFi assemblies reveals centromere diversity between two Arabidopsis thaliana genomes

Fernando Rabanal et al. bioRxiv 480579 doi 10.1101/2022.02.15.480579 (posted February 16, 2022)

Although long-read sequencing can often enable chromosome-level reconstruction of … Read the rest

eLife: Repeated origin of gylphosate resistance in waterhemp

Repeated origins, widespread gene flow, and allelic interactions of target-site herbicide resistance mutations

Julia Kreiner et al., eLife 11:e70242 (2022). doi: 10.7554/eLife.70242

Causal mutations and their frequency in agricultural fields are well-characterized for herbicide resistance. However, we still lack understanding … Read the rest

Now in Nature: Essential genes mutate less

Mutation bias reflects natural selection in Arabidopsis thaliana

Grey Monroe et al., Nature, published online January 12, 2022

Since the first half of the twentieth century, evolutionary theory has been dominated by the idea that mutations occur randomly with respect … Read the rest