In Plant Journal: new microRNA paper on THO2
THO2, core member of the THO/TREX complex, is required for micro RNA production in Arabidopsis
The THO/TREX complex mediates the transport of … Read the rest
Congratulations, Dr. Verena Kottler!
Verena successfully defended per PhD thesis today!
Its title: ‘Pigment cell organization and genetic analysis of color pattern formation in the guppy’
Congratulations, Verena!
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Farewell to Markus
After 15 years in Weigelworld – first as a post-doc in San Diego, later as a group leader in Tübingen – Markus will move North and start his new lab at the Umeå Plant Science Center. We wish you all … Read the rest
Weigelworld Retreat 2015
We spent two days discussing future research directions – follow the link below to see some pictures.
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Nature Review Genetics: Comparative genomics of Arabidopsis relatives
Beyond the thale: comparative genomics and genetics of Arabidopsis relatives.
For decades a small number of model species have rightly occupied a privileged position in laboratory experiments, but it is becoming increasingly clear that our knowledge … Read the rest
Nature Plants: Reduced symmetric DNA methylation in Arabis alpina
Genome expansion of Arabis alpina linked with retrotransposition and reduced symmetric DNA methylation
Willing E. M., Rawat V., Mandáková T., Maumus F., James G. V., Nordström K., Becker C., Warthmann N., Chica C., Szarzynska B., Zytnicki M.,Albani M., Kiefer C., … Read the rest
Plant Journal: Rapid divergence of miRNAs and miRNA targets
Rapid divergence and high diversity of miRNAs and miRNA targets in the Camelineae.
Smith LM, Burbano HA, Wang X, Fitz J, Wang G, Ural-Blimke Y, Weigel D.
MicroRNAs (miRNAs) are short RNAs involved in gene regulation through translational inhibition and … Read the rest
PLoS Genetics: Century-scale Methylomes in Arabidopsis
Century-scale Methylome Stability in a Recently Diverged Arabidopsis thaliana Lineage
There has been much excitement about … Read the rest
G3: Inexpensive GBS, new algorithm for genetic mapping
Rapid and Inexpensive Whole-Genome Genotyping-by-Sequencing for Crossover Localization and Fine-Scale Genetic Mapping
Beth A. Rowan, Vipul Patel, Detlef Weigel, and Korbinian Schneeberger
The reshuffling of existing genetic variation during meiosis is important both during evolution and in breeding. The re-assortment … Read the rest
G3: Plant genetic archaeology: Pedigree of a trisomic line
Whole-Genome Sequencing Reveals the Pedigree of a Classical Trisomic Line
Patrice A. Salomé and Detlef Weigel
The circadian oscillator is astonishingly robust, to changes in the environment, but also to genomic changes that alter the copy number of its components … Read the rest
PLoS Genet: Hybrid incom- patibility & R gene evolution
From collaboration with Alcázar, Koornneef and Parker labs:
Rubén Alcázar, Marcel von Reth, Jaqueline Bautor, Eunyoung Chae, Detlef Weigel, Maarten Koornneef, Jane E. … Read the rest
Current Biology:
miRNA networks & leaf complexity
Temporal Control of Leaf Complexity by miRNA-Regulated Licensing of Protein Complexes
Ignacio Rubio-Somoza, Chuan-Miao Zhou, Ana Confraria, Claudia Martinho, Patrick von Born, Elena Baena-Gonzalez, Jia-Wei Wang, Detlef Weigel
Current Biology 24, 2714–2719
Highlights
•miR319-targeted TCPs … Read the rest
Cell: NLRs as hotspots of deleterious epistasis
Species-wide Genetic Incompatibility Analysis Identifies Immune Genes as Hot Spots of Deleterious Epistasis
Eunyoung Chae, Kirsten Bomblies, Sang-Tae Kim, Darya Karelina, Maricris Zaidem, Stephan Ossowski, Carmen Martín-Pizarro, … Read the rest
PLoS Genet: Evolution of DNA Methylation Patterns
Evolution of DNA Methylation Patterns in the Brassicaceae is Driven by Differences in Genome Organization
Danelle K. Seymour, Daniel Koenig, Jörg Hagmann, Claude Becker, Detlef Weigel
PLoS Genetics Published: November 13, 2014; DOI: 10.1371/journal.pgen.1004785
DNA methylation is an ancient molecular … Read the rest
Genome Res: Hi-res Hi-C analysis in Arabidopsis
Genome Res. 2014 Nov 3. pii: gr.170332.113.
Genome-wide analysis of local chromatin packing in Arabidopsis thaliana.
Wang C, Liu C, Roqueiro D, Grimm D, Schwab R, Becker C, Lanz C, Weigel D.
Genome Res. 2014 Nov 3. pii: gr.170332.113.
The … Read the rest
CHM: Convergence of pathogens on common host proteins
We were able to contribute analyses based on 1001 Genomes data to his exciting project describing how a common set of … Read the rest
SPP1529 Adaptomics projects renewed
Our two projects in the SPP1529 (Research Focus Program of the German Research Council DFG) have been renewed
One on variation in Capsella, with Magnus Nordborg and Barbara Neuffer, and one on adaptation of various Brassicaceae along a steep rainfall … Read the rest
Dissection of miRNA pathways using protoplasts
Mol Plant. 2014 Oct 24. pii: ssu119. [Epub ahead of print]
Dissection of miRNA pathways using Arabidopsis mesophyll protoplasts.
Martinho C, Confraria A, Elias CA, Crozet P, Rubio-Somoza I, Weigel D, Baena-González E.
microRNAs (miRNAs) control gene expression mostly post-transcriptionally … Read the rest
Trowel: superior error correction module for Illumina
Trowel: a fast and accurate error correction module for Illumina sequencing reads.
Lim EC, Müller J, Hagmann J, Henz SR, Kim ST, Weigel D.
Bioinformatics. 2014 Jul 29. pii: btu513. [Epub ahead of print]
MOTIVATION:
The ability to accurately read … Read the rest
A nice entry
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… Read the restNulla consequat massa
