Genome-wide association study published in Nature
Based on the Arabidopsis thaliana haplotype map that we published in 2007, 1200 accessions are currently genotyped with a 250,000 SNP chip by the Bergelson, Borevitz and Nordborg labs.
The data can be found here. The results from performing … Read the rest
80 A. thaliana genome sequences released
The Weigel lab has released the first 80 A. thaliana genome sequences from the 1001 Genomes project.
See the project homepage for details.… Read the rest
Incoming postdoc Dan Koenig wins prestigious HFSP Fellowship
Dan Koenig has won one of the highly competitive Long-Term Fellowships from the Human Frontier Science Program Organization (HFSPO). Dan is finishing his PhD work with Neelima Sinha at UC Davis and join Team Natural Variation in the Weigel lab … Read the rest
Presentation of Otto Bayer Award in Berlin
Today, the Otto Bayer Award was presented at an impressive event at the E-werk in Berlin.
Present were, among others, the chairman of the board of Bayer, Dr. Manfred Schneider, the CEO of Bayer, Werner Wenning, Dr. Wolfgang Plischke, member … Read the rest
Collaboration with Freiburg results in cover of Cell
A very interesting story on Physcomitrella miRNAs guiding DNA methylation at target genes has just been published in Cell, with a cover image.
Stephan Ossowski designed artificial miRNAs, which turned out to provide a small, but useful piece of the … Read the rest
Science paper on spontaneous mutations published
A collaborative paper with the Lynch lab on the rate and spectrum of spontaneous mutations in Arabidopsis thaliana has been published on January 1, 2010, in Science.
The paper provides important information for understanding the longer-term effects of mutation and … Read the rest
Detlef Weigel receives Otto Bayer Award 2010
Detlef Weigel will receive the Otto Bayer Award 2010 of the Bayer Science and Education Foundation.
The award, one of the most important scientific prizes in the German speaking countries, will be presented by the CEO of Bayer, Werner Wenning, … Read the rest
Nino Shervashidze wins NIPS 2009 Award
Nino Shervashidze, PhD student in Karsten Borgwardt’s group, has won the Outstanding Student Paper Award.
Her work was selected from 1105 articles submitted at NIPS, the premier conference in Machine Learning. In her paper, Nino presents a novel algorithm for … Read the rest
Weigel leads citation ranking in plant and developmental biology
The trade magazine Laborjournal regularly publishes rankings comparing the citation records of scientists from the German speaking countries (Austria, Germany, Switzerland).
Across publications that appeared from 2003 to 2006, Detlef Weigel ranked first, by a considerable margin, among both plant … Read the rest
GenomeMapper short read tool published in Genome Biology
Current short read analysis strategies use only a single reference, ignoring previously identified variants.
We have developed a graph mapping approach, that allows simultaneous mapping against all known variants, and thereby greatly increases the number of polymorphisms discovered.Simultaneous alignment of … Read the rest
Identify an EMS lesion in one week–SHOREmap paper published!
Traditional strategies for identification of causal mutations involve two discrete steps: recombinant genotyping and candidate gene sequencing.
To dramatically speed up identification of causative point mutations and small deletions, we provide the software package SHOREmap (http://1001genomes.org/downloads/shore.html), an extension of the … Read the rest
miR156/SPL paper published in Cell
Jia-wei’s paper, reporting the discovery of a new pathway that allows Arabidopsis thaliana to flower in the absence of inductive long days, has just been published in Cell
Back to back with a paper from the Poethig lab, on which … Read the rest
Sabbatical visitor Rod Wing wins prestigious Humboldt Award
Rod is spending a year-long sabbatical in the Department, with the aim of developing new strategies for comparative genomics in both rice and Brassicaceae.
Professor Rod Wing, Director of the Arizona Genomics Institute at the University of Arizona, has won … Read the rest
PNAS paper on rice varation published
We were part of a large international collaboration that used Perlegen ultra-high density microarrays to interrogate 20 diverse landraces and modern varieties of rice.
This work resulted in the first rice HapMap and laid the foundation for large-scale genetic characterization … Read the rest
AENEAS and TRANSNET funded
Two new collaborative projects have recently been funded,
The EU project AENEAS–Acquired environmental epigenetics advances: from Arabidopsis to maize, and the BMBF-GABI project TRANSNET–Transcriptional networks and their evolution in the Brassicaceae.
AENEAS is led by Serena Varotto (Padova), and includes … Read the rest
Detlef Weigel elected to National Academy of Sciences
Detlef Weigel, a naturalized US citizen, was elected to the National Academy of Sciences at their 146th Annual Meeting in Washington, DC.
The National Academy of Sciences is the US’ most prestigious scientific organization, and election to membership in the … Read the rest
PNAS paper on Capsella speciation published
Self-compatible Capsella rubella and -incompatible C. grandiflora are two closely related and crossable species.
Remarkably, we have now found, in collaboration with other groups from the ERA-PG ARelatives consortium, that C. rubella apparently originated from C. grandiflora only a few … Read the rest
Science paper on triplet repeats published
Triplet repeat expansions cause many human genetic diseases. Until now, no naturally occurring triplet repeat associated genetic defects were known from other multicellular species.
We have identified such a case in Arabidopsis thaliana, which provides a convenient genetic model … Read the rest
